Repetitive Transcranial Magnetic Stimulation in a Group of Treament-Resistant Obsessive-Compulsive Disorder Patients: A Descriptive Study

Objective: This study aims to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) treatment in a group treatment-resistant obsessive-compulsive disorder (OCD) patients and examine relationship between various sociodemographic clinical variables response. Materials Methods: Data including The Yale–Brown Obsessive Compulsive Scale (Y-BOCS) scores characteristics 27 OCD who received 30 sessions low-frequency rTMS (LF-rTMS) on left dorsolateral prefrontal cortex (DLPFC) were analyzed. Results: Mean Y-BOCS decreased significantly across week 0 3rd (t(26)=10.59, p<.001) continued decrease weeks 3 6 (t(26)=11.47, p<.001). 21(78%) responders with at least %25 mean scores, 10(47.6%) these 21 also met complete response criteria 35% or more reduction Y-BOCS. No significant difference was observed non-responders regarding variables. only reported side headaches local scalp tenderness, which improved short time. Conclusion: descriptive has demonstrated efficacy long-duration LF-rTMS application DLPFC drug-resistant patients. finding might contribute available literature, especially drawing out standardized protocol cases.